Pantoprazole as the name indicated, they are azoles derivatives, they are the member of proton pump inhibitors (PPIs).
Proton pump inhibitors are indicated for the treatment of stomach ulcer, intestinal ulcers, GERD, esophagitis etc.
The mechanism of pantoprazole is to decrease the acid secretion which is produced by our stomach.
Uses of Pantoprazole
- In the treatment of gastroesophageal reflux disease (GERD)
- In the treatment of heartburn.
- In the treatment of gastric ulcers.
- In the treatment of duodenal ulcers.
- In the treatment of ulcer caused by H. pylori
Pantoprazole is formulated in various dosage forms like it can be formulated in the form of enteric coated tablets, It can be formulated in the form of enteric coated pellets filled in hard gelatin capsules, and it can be also formulated in the form of lyophilized injection.
Lyophilized pantoprazole injection is manufactured by lyophilization process that involves three major steps:
- Deep freeze drying
- Sublimation
- Desorption
There are many advantages of lyophilized pantoprazole injection which increases its demand in market like it have better shelf life, it does not contains water content as it is formulated by sublimation process means direct conversion of solid stage in to vapour stage this makes them free from bacterial growth.
There are many pharmaceutical manufacturers who deal with lyophilized injection manufacturing.
Affy group is one of the organizations, involved in manufacturing of Pantoprazole lyophilized injection. They also manufacture pantoprazole enteric coated tablet, and pantoprazole capsules.
